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Elevated liver enzymes with Crohn’s disease

Alanine transaminase (ALT) and aspartate transaminase (AST) are the common liver values monitored in Crohn’s patients by doctors. These levels are monitored by regular scheduled bloodwork.

These levels can sometimes be elevated due to the harsh drugs used to treat Crohn’s disease. Oral drugs like prednesone are limited in their length of use to avoid injury to the liver. Infliximab (Remicade) has also been cited to cause liver damage.

Alcohol can also increase liver enzyme values. With high liver enzymes it is advised to not drink alcohol.

To treat high liver values, you first need to figure out what’s causing the high levels. You may need to start eating cleaner food, drink less alcohol or lower your bodyweight. The same old advice of eating healthier, exercising, sleeping more and drinking more water applies here.

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